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Yongyuth Yuthavong (Author of Sparks from the Spirit)
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Scaling Biodiversity. Paperback or Sof. Report item - opens in a new window or tab. Seller assumes all responsibility for this listing. Item specifics Condition: Brand New: A new, unread, unused book in perfect condition with no missing or damaged pages. See all condition definitions - opens in a new window or tab Read more about the condition. About this product. Tapping Molecular Wilderness : Drugs from Chemistry—Biology--Biodiversity Interface, Hardcover by Yuthavong, Yongyuth, ISBN , ISBN , Brand New, Free shipping in the US Looks at the broad picture of how materials and organisms from nature affect our health and how we have combined our knowledge in chemistry, biology and biodiversity to promote our wellness from resources in the "molecular wilderness," with caveats on sustainable utilization of these resources.
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Taxes may be applicable at checkout. Learn more. Return policy. Refer to eBay Return policy for more details. You are covered by the eBay Money Back Guarantee if you receive an item that is not as described in the listing. Payment details. This book is for readers with some background in science, concerning the search for drugs, starting from molecular diversity in nature or molecular wilderness.
Drug molecules may be used as such, or as starting points for improved drugs obtained from the interface of chemistry and biology. In some cases, the essential molecular features for drug properties from natural molecules may be identified and modified to more effective ones. In other cases, nature provides the targets, such as essential enzymes from infectious microorganisms, from which synthetic drugs can be designed. The mechanisms of action of drugs can be discerned by studying target-drug interactions.
Of the 27 extracts evaluated, chloroform extracts of Azadirachta indica leaves had the highest activity minimum inhibitory concentration of Other extracts showed activity on the parasite in vitro at concentrations that were much higher than chloroformic extract of A. This study has confirmed the hypothesis that some plants used in Kenya to control trypanosomiasis have trypanocidal potential.
Experimental mice were injected with T. Treated animals were then monitored for parasitaemia starting the following day after treatment. In comparison to suramin, the standard drug, extract of both A.
High activity was found for extract of A. Following this observation, it is recommended that future studies should address purification, structure eluci dation and biochemical characteristic of active components of Azadirachta indica leaves. This study has confirmed the hypothesis that some plants used in control of trypanosomiasis in Kenya have trypnocidal potential.
The objective of the study was to determine the trends in ocular tumours that affect the horse in Kenya and to relate the histological characteristics to the clinico-epidemiological parameters. The study design used the retrospective and prospective suspected cases presented to the Department for histological diagnosis and from which a neoplastic diagnosis of the eye or its adnexa was recorded.
Best Seller Tapping Molecular Wilderness: Drugs from Chemistry-Biology--Biodiversity Interface
The procedure involved retrieval of diagnostic reports from retrospective cases and histopathological examination of both retrospective and prospective cases. Each case was evaluated for the type and frequency of histological lesions and clinicoepidemiological data. Parameters included analyses of age, sex, breed, geographical origin, diagnosis, location of neoplasms, the pathology of the lesion, and the clinical features presented. The histological features were compared between cases and cellular behaviour was correlated with clinico-epidemiological parameters.
The results showed that the most common ocular tumour was squamous cell carcinoma of the adnexa. Occasional diagnosis included melanoma, adenoma, fibroma and lymphoma of the adnexa. In a few cases, non neoplastic growths such as lymphoid hyperplasia of third eyelid were key differential diagnoses.
True ocular tumours were rarely observed. A density-functional theory DFT study of five ruthenium complexes has been carried out with the goal of gaining deeper insight into factors governing luminescence lifetimes.
Experimental work, including the synthesis and photophysical properties of 5 is also reported in the context of this study. Gas phase geometries optimized using X-ray crystallography geometries as start geometries were found to be close to the start geometries. Gas phase absorption spectra calculated using time-dependent DFT were found to be in good agreement with spectra measured in solution. A partial density of states PDOS analysis of the molecular orbitals shows that it is possible to recover a ligand field theory LFT -like picture. These luminescence measures are intended as qualitative rather than quantitative predictors.
Soil moisture storage in the root zone determines availability of water in crop production, but there is limited attention on water resource management in cassava—sorghum production systems. Soil moisture content was higher under ripping than mouldboard ploughing. Mouldboard ploughed plots had more moisture in the upper 0—10 cm layer while, the ripped plots accumulated more moisture in the lower 20—40 cm root zone.
Soil surface roughness was stable two months after ploughing.
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Crop combinations and seasons influenced soil moisture storage over the growing period. The different cropping systems vary in their soil moisture extraction capacities at different growth stages, hence influencing the overall moisture storage and water used in the root zone.
http://maisonducalvet.com/peas-de-san-pedro-dating-agency.php Background: Osteoarthritis OA is one of the most common chronic rheumatic disorders and is associated with significant morbidity and disability. Few studies examined the spectrum of rheumatic diseases in sub- Saharan Africa. Obesity is not only a risk factor for incidence of OA but also for the progression of the disease. Objective: The aim of the study was to determine the patterns of knee, hip and hand osteoarthritis as well as obesity prevalence in the patients with established disease. Methods: A cross-sectional descriptive study, we examined patients with knee, hip and hand osteoarthritis to describe the patterns of osteoarthritis in patients who fulfilled the ACR diagnostic criteria.
Their body mass indices were also studied to determine the prevalence of obesity in this cohort of patients Results: A total of patients with knee, hip or hand osteoarthritis were studied. There were 89 Obesity was more common in participants with knee than in hip OA The bilateral disease was higher in obese Conclusion: Knee OA was very common and the majority of the patients were overweight and obese. Bilateral OA was more prevalent in obese and overweight participants compared to normal weight participants. Obesity is an easily modifiable risk factor for knee OA so it can be made a valid target for preventing as well as halting the progression of OA.
Background: Hepatitis C Virus HCV infection is a worldwide burden whose seroprevalence is higher in developing countries with Cameroon being the third most aff ected country in Africa. HCV both a hepatotropic and lympho- tropic infection is responsible for a great number of hepatic and extra hepatic disorders some of which are rheumatic in nature.
These rheumatologic mani- festations though extensively studied in western countries; there is little or no data in sub-Saharan Africa. Objective: The study was conducted with the aim to describe the musculo- skeletal manifestations associated to HCV infection in a hospital setting in Cameroon. Design: A cross-sectional study. Patients and methods: From February to June , we did a multicentric cross-sectional study of patients from the Gastroenterology, Rheumatology and Internal medicine outpatient clinics of three hospitals in Cameroon. Results: Among patients with HCV infection identifi ed during the study period, only 62 fulfi lled eligibility, 15 HCV infection was discovered during routine medical check-up.
Conclusion: Arthralgia is the most common presenting feature of the symptomatic disease. Musculoskeletal manifestations may be confused with symptoms of common tropical infections, leading to delayed diagnosis and treatment of HCV infection. Cameroon, the third most affected country in Africa, has a seroprevalence which varies from as low as 0. Hepatitis C virus HCV which is a single-stranded, spherical RNA enveloped fl avivirus, measuring 38 to 50 nm in diameter has multiple genotypes and quasispecies classifi ed in six major clades.
This genetic diversity confers to this virus a difference in pathogenicity, disease severity, and response to treatment with interferon3. Design: A cross-sectional descriptive study.